Understanding Neuronal Response to Ischemic Stress

The work in this laboratory concerns protein biosynthesis in neural cells. We are interested in how neurons produce proteins with proper function, at the right time and in the right location; and, how protein biosynthesis may modulate the neuronal response to various stresses. Current research focuses on protein actutators of neuronal ischemic injury and its prevention.

Neurons are sensitive to ischemic stress and vulnerable to ischemic cell death. In the brain, prolonged ischemia will result in massive tissue injury, as seen in ischemic stroke (one of the most devastating neuronal disorders in the North America), whereas in eye, retinal ischemia may trigger glaucomatous changes or other vision disorders.
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Laboratory Members

An Zhou, Ph.D., Principal Investigator
Fang Bian, Ph.D., Research Associate
Li Cao, Ph.D., Research Associate
Yun Li, M.D., Research Assistant
Kefeng Xu, M.S., M.D., Research Associate

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