| || Understanding Function Changes in Nerve Cell Circuitry in Aging and Disease |
Learning is dependent on the ability to store memories. Although neuroscientists have discovered much about how nerve cells transmit signals, the connection between signal transmission and memory storage still eludes us. Storage of memory may be dependent on how easily rapid electrical signals travel from one nerve cell to another. We know that learning sometimes requires repetition. Likewise, repetitive electrical activity over the same circuitry pathway may strengthen or weaken functional connections between nerve cells.
Difficulties in learning (cognitive deficits) occur in a wide variety of neurological disorders such as epilepsy, traumatic brain injury, Alzheimer Disease. Also, learning difficulties can plague some of the elderly. We study how electrical signaling through neuronal circuitry in the brain changes over lifespan and in disease models. [read more] Laboratory Members
Morris Benveniste, Ph.D.
Ezekiel Carpenter-Hyland, Ph.D.
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