The Analytical Chemistry and Protein Profiling Core is comprised of three primary labs:
Analytical Chemistry Lab (ACL) provides custom analytical support for clinical, basic and transitional research. The services that the ACL routinely performs include analysis via: 1) HPLC and 2) ELISA and colorimetric testing. Analysis by GC/MS-EI (drugs, anabolic steroids) is available by special request. In addition to providing analytical support, the ACL provides consults on analytical techniques, sample requirements, etc. to the investigators throughout the project (from concept to completion).
Protein Profiling Lab offers services such as protein identification and analysis of protein modifications. It houses a Surface Enhanced Laser Desorption-Ionization (SELDI) mass spectrometer, and a Thermo-Finnigan LTQ LC/MS/MS system. SELDI is a mass spectrometry technique used to analyze proteins and other complex mixtures of biomolecules. This core lab also has a BioPlex bead sorter, which allows the analysis of multiplex assays such as ELISAs from a single, small volume sample.
2D Gel Electrophoresis Lab works in conjunction with the Protein Profiling lab and offers differential protein expression analysis by both gel and LC analysis. Within this lab is a BioRad automated spot picker (Proteome Works) and a BioRad gel imager (Molecular imager FX).
For more information and service charges, contact:
Dr. Michael Powell
Proteomics Core Leader
Phone: (404) 752-1582
Dr. Winston Thompson
2D Gel Electrophonesis Core Leader
Phone: (404) 752-1715