<?xml version="1.0" encoding="UTF-8"?><profile href="/about_us/FacultyDirectory/Neurobiology/TiandongLeng/index.php">
   <image><img src="/_resources/MSMimages/FacultyDirectoryImages/Neurobiology/TiandongLeng2023.jpg" alt="Tiandong Leng, M.D., Ph.D."></img></image>
   <name>Tiandong Leng, M.D., Ph.D.</name>
   <title>Professor</title>
   <department>Neurobiology</department>
   <title2></title2>
   <department2></department2>
   <email>tleng@msm.edu</email>
   <phone>(404) 756-6698</phone>
   <location>Multidisciplinary Research Center 218</location>
   <education><strong>MEDICAL SCHOOL:<br></br></strong>Weifang Medical University<strong><br></br></strong><strong>Degree: </strong>Doctor of Medicine<br></br><br></br><strong><strong>GRADUATE:<br></br></strong></strong>Sun Yat-Sen University<strong><strong><br></br></strong></strong><strong>Degree: </strong>Doctor of Philosophy in Pharmacology</education>
   <research>
      <ul>
         <li>Stroke</li>
         <li>Ion channel</li>
         <li>CNS Drug Development</li>
      </ul>
   </research>
   <boardcerts></boardcerts>
   <publications>
      <ul>
         <li>Huawei Sun, Tao Yang, Roger Simon, Zhi-gang Xiong, <strong>Tiandong Leng#.</strong> The role of cholesterol metabolic enzyme CYP46A1 and its metabolite 24S-hydroxycholesterol
            in ischemic stroke. Stroke 2024 Sep 3. doi: 10.1161/STROKEAHA.124.047803 (#corresponding
            author)</li>
         <li>Huawei Sun, Tao Yang, Roger Simon, Zhi-gang Xiong, <strong>Tiandong Leng#</strong>. Cholestane-3β, 5α, 6β-triol inhibits ASICs and protects against acidosis-mediated
            ischemic brain injury. Stroke 2024 Apr 25. doi: 10.1161/STROKEAHA.124.046963 (#corresponding
            author).</li>
         <li>Baoming Wu, Jaree Bargaineer, Ling Zhang, Tao Yang, Zhigang Xiong and <strong>Tiandong Leng#. </strong>Upregulation of acid sensing ion channel 1a (ASIC1a) by hydrogen peroxide through
            JNK pathway, Acta Pharmacol 2021 Aug;42(8):1248-1255. (#corresponding author)</li>
         <li>Yan M, Liu AL, Zhou SJ, Tang LP, Ou YQ, Yin W, Chen XY, Su XW, Qiu PX, Huang YJ, Zhang
            JX, Yan GM, <strong>Leng TD#. </strong>Characterization of a synthetic 24-keto-cholest-5-en-3 , 19-Diol as a neuroprotectant.
            CNS Neuroscience&amp;Therapeutics. 2015 Jun;21(6):486-95 (#corresponding author)</li>
         <li>Hu HY*, Zhou YH*, <strong>Leng TD*, </strong>Liu AL, Wang YQ, Yin W, Huang YJ, Zhang JX, Qiu PX, Wang LW, Sang HF and Yan The major
            cholesterol metabolite cholestane-3 , Sa, 6 -triol functions as an endogenous neuroprotectant.
            J Neurosci. 2014 Aug 20;34(34):11426-38 (*equal contribution)</li>
      </ul>
      <p>Click to view additional publications: <a href="https://pubmed.ncbi.nlm.nih.gov/?term=tiandong+leng">https://pubmed.ncbi.nlm.nih.gov/?term=tiandong+leng</a></p>
   </publications>
   <awards></awards>
</profile>